Statistical Bioinformatics Lab
About me
Department of Population & Quantitative Health Sciences
School of Medicine
Case Western Reserve University
10900 Euclid Avenue
SOM / Room G82T
Cleveland, OH 44106
USA
Bio
I am is a tenure-track assistant professor in biostatistics at the Department of Population & Quantitative Health Sciences at Case Western Reserve University School of Medicine and an associate member at Case Comprehensive Cancer Center (Case CCC).
I obtained my Ph.D. degree (2019) in Biostatistics from Emory University under the guidance of professor Hao Wu. Before that, I received my MSPH degree (2013) in biostatistics from Emory University and my BS degree (2011) in biosciences from the University of Science and Technology of China.
I am a statistician focusing on problems in bioinformatics. Developing statistical methods for high-throughput omics data is a major component of my research. I (co-)developed statistical methods DSS to identify Differentially Methylated Regions (DMR) in Bisulfite-sequencing (BS-seq) data, InfiniumPurify to identify cancer subtypes using DNA methylation microarray data, cfDNAmethy to deconvolute cell-free DNA methylation signal in plasma using liquid biopsy. I collaborate closely with physicians and wet-lab researchers on various projects including cancer, virus, trauma, epidemiology and neurodegenerative disease studies.